The Pseudomonas Quinolone Signal (PQS): Not Just for Quorum Sensing Anymore

Conversion of the Pseudomonas aeruginosa Quinolone Signal ( PQS ) and Related

The Pseudomonas quinolone signal regulates rhl quorum sensing in Pseudomonas aeruginosa.

The opportunistic pathogen Pseudomonas aeruginosa uses intercellular signals to control the density-dependent expression of many virulence factors. The las and rhl quorum-sensing systems function, respectively, through the autoinducers N-(3-oxododecanoyl)-L-homoserine lactone and N-butyryl-L-homoserine lactone (C(4)-HSL), which are known to positively regulate the transcription of the elastase-...

The Pseudomonas Quinolone Signal (PQS) Balances Life and Death in Pseudomonas aeruginosa Populations

When environmental conditions deteriorate and become inhospitable, generic survival strategies for populations of bacteria may be to enter a dormant state that slows down metabolism, to develop a general tolerance to hostile parameters that characterize the habitat, and to impose a regime to eliminate damaged members. Here, we provide evidence that the pseudomonas quinolone signal (PQS) mediate...

PqsE functions independently of PqsR-Pseudomonas quinolone signal and enhances the rhl quorum-sensing system.

Pseudomonas aeruginosa is an opportunistic pathogen that causes both acute and chronic infections in immunocompromised individuals. This gram-negative bacterium produces a battery of virulence factors that allow it to infect and survive in many different hostile environments. The control of many of these virulence factors falls under the influence of one of three P. aeruginosa cell-to-cell sign...

Correction: Dynorphin Activates Quorum Sensing Quinolone Signaling in Pseudomonas aeruginosa

Pseudomonas aeruginosa Olga Zaborina, Francois Lepine, Gaoping Xiao, Vesta Valuckaite, Yimei Chen, Terry Li, Mae Ciancio, Alex Zaborin, Elaine O. Petrof, Jerrold R. Turner, Laurence G. Rahme, Eugene Chang, John C. Alverdy doi: 10.1371/journal.ppat.0030035 In PLoS Pathogens, vol 3, issue 3: One of the authors, Dr. Elaine O. Petrof, was incorrectly listed as Elaine Petroff. This correction note m...